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林彥亨

林彥亨教授   電子工程學系

    

信箱:yenheng@mail.cgu.edu.tw

電話:03-2118800 ext.3789

最高學歷:成功大學工程科學博士

專長領域:超快速PCR生醫晶片平台開發單細胞分析平台開發生醫晶片設計及製作;微機電製程技術

個人/實驗室網頁:https://sites.google.com/site/bolcgu/

研究主題

超快速PCR生醫晶片平台開發、單細胞分析平台開發、生醫晶片設計及製作、微機電製程技術

發表著作

Updated 2023/02/22

Journal paper:

Sum of the Times Cited: 1629 (Scopus database)

h-index: 21

A24. Yen-Heng Lin*, Xiang-Jun Liao, Wei Chang, and Chiuan-Chian Chiou, Ultrafast DNA amplification using microchannel flow-through PCR device, Biosensors, Vol. 12, 303, 2022.

A23. Ding-Ping Chen, Chen Chen, Pei-Yu Wu, Yen-Heng Lin*, Wei-Tzu Lin, Yi-Liang Yan, Micro-droplet platform for exploring the mechanism of mixed field agglutination in B3 subtype, Biosensors, Vol. 11, 276, 2021.

A22. Yen-Heng Lin*, Ching-Hui Chang, Glass capillary assembled microfluidic three-dimensional hydrodynamic focusing device for fluorescent particle detection, Microfluidics and Nanofluidics, Vol. 25, 42, 2021.

A21. Yen-Heng Lin*, Chia-Chun Wu, Wei-Ting Su, Pei-Chi Tseng, Ya-Yu Hsueh, Yung-Chin Hsiao, Kai-Ping Chang, Jau-Song Yu*, Yun-Ju Chuang, Target peptide enrichment microfluidic chip for rapid detection of oral squamous cell carcinoma using stable isotope standards and capture by anti-peptide antibodies, Sensors and Actuators B: Chemical, Vol. 322, 128607, 2020.

A20. Yen-Heng Lin*, Chih-Ching Wu, Wan-Ling Chen, Kai-Ping Chang, Anti-p53 autoantibody detection in automatic glass capillary immunoassay platform for screening of oral cavity squamous cell carcinoma, Sensors, Vol. 20, 971, 2020.

A19. Yen-Heng Lin*, Heng-Yun Chang, Chia-Chun Wu, Chia-Wei Wu, Kai-Ping Chang, Jau-Song Yu*, BRAF protein immunoprecipitation, elution, and digestion from cell extract using a microfluidic mixer for mutant BRAF protein quantification by mass spectrometry, Analytical and Bioanalytical Chemistry, Vol. 411, 1085–1094, 2019.

A18. Yen-Heng Lin*, Chih-Ching Wu, Yong-Sheng Peng, Chia-Wei Wu, Ya-Ting Chang, Kai-Ping Chang, Detection of anti-p53 autoantibodies in saliva using microfluidic chips for the rapid screening of oral cancer, RSC Advances, Vol. 8, 15513–15521, 2018.

A17. Yen-Heng Lin*, Jing-Chao Wong, Yong-Sheng Peng, Characterization of the Electrical Properties of Silicon Nanowire using the Dielectrophoretic Assembling Platform, International Journal of Electrochemical Science, Vol. 12, 2017.

A16. Yen-Heng Lin*, Wei-Siao Lin, Jing-Chao Wong, Wei-Chieh Hsu, Yong-Sheng Peng, Chien-Lun Chen, Bottom-up assembly of silicon nanowire conductometric sensors for the detection of apolipoprotein A1, a biomarker for bladder cancer, Microchim Acta, Vol. 184, 2419–2428, 2017.

A15. Yen-Heng Lin*, I.-Chi Lee, Wei-Chieh Hsu, Ching-Hong Hsu, Kai-Ping Chang, Shao-Syuan Gao, Rapid fabrication method of a microneedle mold with controllable needle height and width, Biomedical Microdevices, Vol. 18, 85, 2016.

A14. Yen-Heng Lin*, Chih-Pin Chu, Chen-Fu Lin, Hsin-Hao Liao, Hann-Huei Tsai, Ying-Zong Juang, Extended-gate field-effect transistor packed in micro channel for glucose, urea and protein biomarker detection, Biomedical Microdevices, Vol. 17, 111, 2015.

A13. Yen-Heng Lin* and Po-Yu Peng, Semiconductor sensor embedded microfluidic chip for protein biomarker detection using a bead-based immunoassay combined with deoxyribonucleic acid strand labeling, Analytica Chimica Acta, Vol. 869, 34-42, 2015.

A12. Yen-Heng Lin*, Kai-Siang Ho, Chin-Tien Yang, Jung-Hao Wang, and Chao-Sung Lai*, A highly flexible platform for nanowire sensor assembly using a combination of optically induced and conventional dielectrophoresis, Optics Express, Vol. 22, pp. 13811-13824, 2014.

A11. Briliant Adhi Prabowo, Ying-Feng Chang, Yu-Ying Lee, Li-Chen Su, Chih-Jen Yu, Yen-Heng Lin, Chien Chou, Nan-Fu Chiu, Hsin-Chih Lai*, and Kou-Chen Liu*, Application of an OLED integrated with BEF and giant birefringent optical (GBO) film in a SPR biosensor, Sensors and Actuators B: Chemical, Vol. 198, pp. 424-430, 2014.

A10. Yen-Heng Lin*, Chia-Chu Wang, and Kin Fong Lei, Bubble-driven mixer integrated with a microfluidic bead-based ELISA for rapid bladder cancer biomarker detection, Biomedical Microdevices, Vol. 16, pp. 199-207, 2014.

A9. Anirban Das, Yen-Heng Lin*, and Chao-Sung Lai*, Miniaturized amorphous-silicon based chemical imaging sensor system using a mini-projector as a simplified light-addressable scanning source, Sensors & Actuators: B. Chemical, Vol. 190, pp. 664-672, 2014.

A8. Yen-Heng Lin*, Anirban Das, and Chao-Sung Lai*, A simple and convenient set-up of light addressable potentiometric sensors (LAPS) for chemical imaging using a commercially available projector as a light source, International Journal of Electrochemical Science, Vol. 8, pp. 7062-7074, 2013.

A7. Yen-Heng Lin*, Anirban Das, Min-Hsien Wu, Tung-Ming Pan, and Chao-Sung Lai*, “Microfluidic Chip Integrated with an Electrolyte-Insulator-Semiconductor Sensor for pH and Glucose Level Measurement,” International Journal of Electrochemical Science, Vol. 8, pp. 5886-5901, 2013.

A6. Yen-Heng Lin*, Ying-Ju Chen, Chao-Sung Lai*, Yi-Ting Chen, Chien-Lun Chen, Jau-Song Yu, and Yu-Sun Chang, “A negative-pressure-driven microfluidic chip for the rapid detection of a bladder cancer biomarker in urine using bead-based ELISA,” Biomicrofluidics, Vol. 7, pp. 024103, 2013.

A5. Atanu Das, Anirban Das, Liann-Be Chang*, Chao-Sung Lai, Ray-Ming Lin, Fu-Chuan Chu, Yen-Heng Lin, Lee Chow, and Ming-Jer Jeng, “GaN Thin Film Based Light Addressable Potentiometric Sensor for pH Sensing Application,” Applied Physics Express, Vol. 6, pp. 036601, 2013.

A4. Song-Bin Huang, Min-Hsien Wu, Yen-Heng Lin, Chia-Hsun Hsie, Chih-Liang Yang, Hung-Chih Lin, Ching-Ping Tseng*, and Gwo-Bin Lee*, “High-purity and label-free isolation of circulating tumor cells (CTCs) in a microfluidic platform by using optically-induced-dielectrophoretic (ODEP) force,” Lab on a chip, Vol. 13, pp. 1371-1383, 2013.

A3. Yen-Heng Lin*, Shih-Hao Wang, Min-Hsien Wu, Tung-Ming Pan, Chao-Sung Lai, Ji-Dung Luo, and Chiuan-Chian Chiou, “Integrating solid-state sensor and microfluidic devices for glucose, urea and creatinine detection based on enzyme-carrying alginate microbeads,” Biosensors and Bioelectronics, Vol. 43, pp. 328-335, 2013.

A2. Yen-Heng Lin, Ya-Wen Yang, Yi-Dao Chen, Shih-Siou Wang, Yu-Han Chang*, and Min-Hsien Wu*, “The application of an optically switched dielectrophoretic (ODEP) force for the manipulation and assembly of cell-encapsulating alginate microbeads in a microfluidic perfusion cell culture system for bottom-up tissue engineering,” Lab on a chip, Vol. 12, pp. 1164-1173, 2012.

A1. Yen-Heng Lin*, Chien-Hung Chiang, Min-Hsien Wu, Tung-Ming Pan, Ji-Dung Luo, and Chiuan-Chian Chiou, “Solid-state sensor incorporated in microfluidic chip and magnetic-bead enzyme immobilization approach for creatinine and glucose detection in serum,” Applied Physics Letters, Vol. 99, pp. 253704, 2011.

C1. “超快速PCR微流道晶片技術” 發明人:林彥亨, 簽約金 220萬元, 2019.(目前實收技轉金額100萬元)

C2. “自動化血液檢測之微流體晶片及其使用方法,” 發明人:林彥亨、陳定平, 申請人:長庚大學, 專利證號:I678536, 2019.

榮譽事項

  1. 指導大學部專題生洪嘉擇、黃冠博參加臺北創新實驗室20X23 天使選秀會&創業者年會 投創金點子組 優勝
  2. 指導大學部專題生洪嘉擇、黃冠博參加2022 第六屆全國醫學工程創意競賽 大專組 佳作
  3. 指導大學部專題生洪嘉擇、黃冠博參加2022 長庚大學【庚新盃】校園創新創業競賽 第三名
  4. 指導大學部專題生曾沛淇同學參加2019 ICSS 獲Honorary Poster Award。
  5. 指導彭詠聖同學參加第十五屆(2017)台塑關係企業應用技術研討會, 以”自體免疫抗體檢測之微流體晶片應用於口腔癌快速篩檢” 獲學校組優勝獎。
  6. 指導大學部專題生徐敬泓學參加2016 旭泰科技論文獎,以”X-Y-Z 平台應用於快速製作經皮藥物釋放微針陣列”獲優良創意獎。
  7. 指導大學部專題生徐敬泓同學參加2016 中國工程師學會學生分會工程論文競賽,以”可控制針高和底寬微針陣列模具的快速製作方法”獲佳作獎。
  8. 指導彭詠聖同學參加2015 生物醫學工程科技研討會,以”自體免疫抗體檢測之微流體檢測晶片應用於快速篩檢口腔癌” 獲壁報論文競賽生醫感測組優等獎。
  9. 指導吳家瑋同學參加2015 化學感測器協會研討會,以”結合微流體及質譜分析技術實現生物標記樣品之 快速前處理應用於癌症診斷及預後評估”獲口頭論文競賽佳作獎。
  10. 指導蘇瑋婷同學參加2015 化學感測器協會研討會,以”多種胜肽質譜樣品前處理之微流體晶片應用於快速癌症篩檢”獲口頭論文競賽佳作獎。
  11. 指導何凱翔同學參加2013SEMBA 生醫工程應用研討會,以”A new platform for assembling nanowire sensor by using combination of optically switched dielectrophoresis and dielectrophoresis” 獲大會最佳論文獎。
  12. 指導彭柏祐同學參加2013 全研科技碩士論文獎,以”免疫分析電晶體結合創新DNA 標記應用於快速膀胱癌之檢測” 獲優良創意作品獎。
  13. 指導何凱翔同學參加2012全國奈米科技應用創意競賽, 以”光介電泳力應用於奈米線感測元件之組裝” 獲銀牌獎。
  14. 指導王嘉駒同學參加2012生物醫學工程科技研討會,以”高效率氣泡混合微流體裝置結合磁珠式酵素連結免疫分析法應用於膀胱癌之檢測” 獲壁報論文競賽優等獎。
  15. 指導王世豪同學參加第十五屆奈米工程暨微系統技術研討會,以”血糖、尿素、肌酐酸ISFET微流體感測晶片” 獲大會最佳論文獎。
  16. 指導王世豪同學參加第九屆台塑關係企業應用技術研討會, 以”新式酵素固定技術應用於EIS微流體血糖感測晶片” 獲學校組績優獎。